the picture is part of a bigger poster of 狗神樂隊 (a rock & roll band) in shanghai, their web site is here:
the three big black character is "不易滚". two small red characters in the "seal" is "狗" (dog) and an inverted "神" (god).
滚 (u+6eda) is a variant character of 滾 (u+6efe)
rock & roll in chinese is 搖滾樂.
need more elaboration?